Cristiano Ronaldo is likely to be benched this evening, with Nicolò Fagioli getting the midfield nod for Juventus, while Lazio can use Adam Marusic in defence.
It kicks off at 19.45 GMT, you can follow all the build-up and action as it happens on the LIVEBLOG.
There are numerous problems for both coaches to deal with ahead of crucial Champions League fixtures.
Cristiano Ronaldo is likely to be benched this evening, with Nicolò Fagioli getting the midfield nod for Juventus, while Lazio can use Adam Marusic in defence.
It kicks off at 19.45 GMT, you can follow all the build-up and action as it happens on the LIVEBLOG.
There are numerous problems for both coaches to deal with ahead of crucial Champions League fixtures.
Sources close to the Juve camp have told Football Italia that Ronaldo is not 100 per cent fit and could even have been left out of the squad entirely.
Alvaro Morata is therefore expected to start with Dejan Kulusevski and Federico Chiesa, while Under-23 player Fagioli could be given the nod in midfield.
Matthijs de Ligt, Giorgio Chiellini and Paulo Dybala are injured, Gianluca Frabotta suspended and Rodrigo Bentancur has COVID.
There are big changes at Lazio too, because Manuel Lazzari joins Luiz Felipe and Stefan Radu on the treatment table.
It’s reported Simone Inzaghi will revamp his back three, introducing wing-back Adam Marusic with Wesley Hoedt and Francesco Acerbi.
Probable line-ups
Juventus: Szczesny; Cuadrado, Demiral, Danilo, Alex Sandro; Ramsey, Rabiot, Fagioli, Chiesa; Kulusevski, Morata
Lazio: Reina; Marusic, Hoedt, Acerbi; Lulic, Milinkovic-Savic, Leiva, Luis Alberto, Fares; Correa, Immobile
Ref: Massa