Here are all the clubs qualified for the quarter-finals in the Champions, Europa and Conference League, with six Italian clubs still involved across the three European competitions.
Italian clubs will know their opponents during a draw that will take place in Nyon on Friday.
Milan, Inter and Napoli have qualified for the Champions League Round of 16 and could meet Real Madrid, Bayern Munich, Chelsea, Benfica or Manchester City.
Teams from the same country can meet at this stage, so there could be an Italian derby or specifically a Derby della Madonnina in the quarter-finals.
Juventus and Roma could also meet in the Europa League quarter-finals and will be joined in Friday’s draw by Manchester United, Sevilla and Feyenoord, Union Berlin, Bayer Leverkusen and Sporting CP.
The Portuguese side eliminated Premier League leaders Arsenal on penalties.
Fiorentina are the only Serie A club left in the Conference League after Lazio‘s elimination at the hands of AZ Alkmaar.
Lech Poznan, Basel, Anderlecht, OGC Nice, Gent and West Ham are the possible opponents for the Tuscans who beat Turkish Sivasspor 5-1 on aggregate over the two legs.
Champions League quarter-finalists
Bayern Munich (GER)
Benfica (POR)
Chelsea (ENG)
Inter (ITA)
Manchester City (ENG)
Milan (ITA)
Napoli (ITA)
Real Madrid (ESP)
Europa League quarter-finalists
Sporting CP (POR)
Bayer Leverkusen (GER)
Feyenoord (NED)
Juventus (ITA)
Manchester United (ENG)
Roma (ITA)
Sevilla (ESP)
Union SG (BEL)
Conference League quarter-finalists
Anderlecht (BEL)
AZ Alkmaar (NED)
Basel (SUI)
Fiorentina (ITA)
Gent (BEL)
Lech Poznan (POL)
Nice (FRA)
West Ham United (ENG)