Juventus are forced to transform their defence without first-choice full-backs, while Milan have a choice to make between Samu Castillejo and Brahim Diaz.
The game is due to kick off on Wednesday at 19.45 GMT, click here for a match preview.
Juventus are forced to transform their defence without first-choice full-backs, while Milan have a choice to make between Samu Castillejo and Brahim Diaz.
The game is due to kick off on Wednesday at 19.45 GMT, click here for a match preview.
There is some concern that the two COVID-19 cases which appeared over the last 24 hours for Alex Sandro and Juan Cuadrado could lead to a travel ban on the Juve squad.
The local health authority (ASL) has stated it could intervene if there were more cases, but not after just two.
If Juventus do play tomorrow evening, then they’ll be without Alex Sandro and Cuadrado, as well as injured Alvaro Morata.
This leaves Andrea Pirlo without first-choice full-backs, so Merih Demiral could be used on the right in this emergency situation.
Another alternative for a more attacking approach would be Gianluca Frabotta, with Danilo on the left.
Federico Chiesa and Aaron Ramsey are the favourites on the wings, around Rodrigo Bentancur and returning Adrien Rabiot, with Paulo Dybala shaking off a fever to start alongside Cristiano Ronaldo.
Serie A leaders Milan have Sandro Tonali suspended, but Theo Hernandez returns to the fold after sitting out a ban against Benevento.
Zlatan Ibrahimovic, Ismael Bennacer, Alexis Saelemaekers and Matteo Gabbia are still injured.
The only real doubt for Stefano Pioli should be in the trio supporting striker Rafael Leao, as Samu Castillejo is challenging Brahim Diaz for a starting spot with Hakan Calhanoglu and Ante Rebic.
Rade Krunic is the only real alternative in midfield to partner Franck Kessie in the absence of both Tonali and Bennacer.
Milan: G Donnarumma; Calabria, Kjaer, Romagnoli, Theo Hernandez; Krunic, Kessie; Castillejo, Calhanoglu, Rebic; Leao
Juventus: Szczesny; Demiral, Bonucci, De Ligt, Danilo; Chiesa, Bentancur, Rabiot, Ramsey; Dybala, Ronaldo