Juventus defender Giorgio Chiellini will take no part in Italy’s upcoming games against Brazil and Malta.
The stopper has been struggling with ankle issues this week which had placed him into doubt for the ties.
After monitoring his situation over the last two days, the decision has been taken by Azzurri doctors to send Chiellini back to his club.
Italy face Brazil in a friendly on Thursday, while they will travel to Malta for a World Cup qualifier next Tuesday.
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's World Cup tipster competition  - £10,000 to be won!