Lazio have rotated their squad to take on Fiorentina this evening with Libor Kozak and Sergio Floccari taking on Alberto Gilardino.
The 17.00 UK time kick-off at the Stadio Olimpico sees Coach Sinisa Mihajlovic pay visit to his former club.
Edy Reja has rotated the squad by resting Hernanes and Giuseppe Sculli ahead of the midweek round, opting for Kozak and Floccari up front.
Some changes were forced, as Mauro Zarate and Andre Dias sit out bans, while Mark Bresciano, Mourad Meghni and Tommaso Rocchi are injured.
Fiorentina pick Gulan in defence, while Alessio Cerci and Adem Ljajic flank Gilardino in a trident attack.
Manuel Pasqual is suspended with Juan Manuel Vargas, Cesare Natali, Sebastien Frey and Stevan Jovetic on the treatment table.
The Viola do have new signings Neto and Valon Behrami – a former Lazio player – on the bench.
Lazio: Muslera; Lichtsteiner, Diakitè, Biava, Radu; Gonzalez, Brocchi, Ledesma, Mauri; Kozak, Floccari
Lazio bench: Berni, Scaloni, Hernanes, Stendardo, Foggia, Sculli, Cavanda
Fiorentina: Boruc; De Silvestri, Kroldrup, Gamberini, Gulan; Santana, Donadel, Montolivo; Cerci, Gilardino, Ljajic
Fiorentina bench: Neto, Babacar, D'Agostino, Comotto, Camporese, Marchionni, Behrami
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's World Cup tipster competition - £10,000 to be won!