Libor Kozak was sent off for Lazio as Bologna were made to rue a host of missed chances in their 0-0 draw.
The Biancocelesti's leading goalscorer Miroslav Klose was fit enough only for the bench as they took on Stefano Pioli's side at Renato Dall'Ara.
Kozak was asked to lead the line for the capital club as they looked for the three points that would take them into the top four, but it was the home team's front players who dominated early on.
Alessandro Diamanti went close inside five minutes with a close-range volley and Saipher Taider powered an effort wide from outside the area.
Vladimir Petkovic's men were not to be outdone though, as Antonio Candreva ghosted into the area, only to force Federico Agliardi into a smart save.
Still the Aguile came forward looking for the opener - but a mixture of good defending from the Rossoblu and poor finishing meant they were unable to craft any real clear-cut chances.
After the interval, it was the hosts who carved out the clearest of opportunities early on, as Taider pounced on a Diamanti pass but couldn’t shoot past Federico Marchetti.
The Felsenei were causing problems with their crowded midfield harrying the Roman side, and they should have opened the scoring midway through the half, but Rene Krhin’s low cross couldn’t find a target.
Kozak was sent off late on for a second bookable offence, but the man advantage didn’t help Bologna as they failed to make their extra man count.
Sent off: Kozak 86 (L)