The first Derby di Verona in 11 years also has Eugenio Corini returning to the Chievo bench aiming to end a perfect Hellas home record.
It kicks off at the Stadio Bentegodi at 17.00 GMT, click here for a match preview.
This fixture has only ever been played in one Serie A season, back in 2001-02, when Verona won 3-2 at home and lost 2-1 away.
Hellas Verona are flying high and will remain at least sixth this weekend regardless of the result.
Confidence could not be better for Andrea Mandorlini, who has a full squad at his disposal and a 100 per cent record on home turf.
Luca Toni leads the trident with Juan Manuel Iturbe and Juan Ignacio Gomez Taleb, plus Jorginho pulling the midfield strings.
The atmosphere over at Chievo is very different, as they are bottom of the table and fired Coach Giuseppe Sannino to bring back Corini.
Veteran Sergio Pellissier begins a two-match ban for insulting officials, while Claiton Dos Santos and Calello are sidelined.
Corini opts for Cyril Thereau as the lone centre-forward with support from Alessio Sestu and Marcelo Estigarribia on the wings.
Hellas Verona: Rafael; Romulo, Maietta, Moras, Albertazzi; Jorginho, Donati, Hallfredsson; Gomez, Toni, Iturbe
Verona bench: Mihaylov, Laner, Martinho, Cacia, Jankovic, Cirigliano, Gonzalez, Marques, Sala, Cacciatore, Donadel, Agostini
Chievo: Puggioni; Frey, Dainelli, Cesar, Dramè; Sestu, Radovanovic, Rigoni, Hetemaj, Estigarribia; Thereau
Chievo bench: Squizzi, Silvestri, Bernardini, Kupisz, Lazarevic, Pamic, Sardo, Acosty, Papp, Paloschi, Ardemagni, Da Silva
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's World Cup tipster competition - £10,000 to be won!