Kevin Strootman and Gervinho start with Adem Ljajic on the bench as Roma host giant-killers Hellas Verona.
The Sunday action in Italy kicks off at 17.00 UK time (16.00 GMT). Click here for a match preview.
The Giallorossi won their season opener 2-0 away to Livorno and now face the home crowd, though more protests are expected after Erik Lamela’s €30m move to Tottenham.
Dutch international Strootman gets his debut after missing last week’s game with an ankle injury, while new signing Ljajic is on the bench following his transfer from Fiorentina.
Ex-Arsenal forward Gervinho came on as a substitute in Livorno, but gets his first start here.
Mattia Destro is out injured and Tin Jedvaj still out due to red tape issues.
The Curva Sud is locked down for one game as punishment for racist chanting against Mario Balotelli at the end of last season.
Verona are back in Serie A for the first time in 12 years and began with a bang, fighting back to beat Milan 2-1 with a Luca Toni brace.
The veteran ex-Roma striker leads the way again with Martinho and Bosko Jankovic in support.
Alessandro Agostini, Daniele Ragatzu and Michelangelo Albertazzi are unavailable.
Roma: De Sanctis; Maicon, Benatia, Castan, Balzaretti; Pjanic, De Rossi, Strootman; Florenzi, Gervinho, Totti
Roma bench: Lobont, Skorupski, Torosidis, Burdisso, Romagnoli, Dodò, Bradley, Taddei, Caprari, Marquinho, Ljajic, Borriello
Verona: Rafael; Romulo, Maietta, Moras, Cacciatore; Hallfredsson, Donati, Jorginho; Jankovic, Toni, Martinho
Verona bench: Nicolas, Mihaylov, Laner, Longo, Cacia, Bianchetti, Cirigliano, Gomez Taleb, Gonzalez, Sala
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's tipster competition - £11,000 to be won monthly!