Napoli start Lorenzo Insigne and Goran Pandev against Chievo, as Edinson Cavani is out of action, but Sergio Pellissier also failed a fitness test.
Cavani pulled up during training with a thigh problem and failed a fitness test this morning, so is in the stands of the San Paolo.
The Partenopei therefore look to Insigne and Pandev to revive their fortunes after two straight defeats in the space of a week against Juventus and Dnipro.
Chievo have traditionally caused problems for Napoli, so will be eager to take advantage for another upset.
Alberto Paloschi, Bostjan Cesar, Gennaro Sardo and Lorenzo Squizzi are out of action.
Hitman Pellissier was expected to be back in the starting XI, but failed a last-minute fitness test and so Marco Rigoni partners Cyril Thereau in a 4-4-1-1 system.
Napoli: De Sanctis; Campagnaro, Cannavaro, Gamberini; Maggio, Behrami, Inler, Zuniga; Hamsik; Insigne, Pandev
Chievo: Sorrentino; Frey, Dainelli, Andreolli, Dramé; Luciano, L Rigoni, Hetemaj, Vacek; M Rigoni; Thereau
Think you know your Italian football? Share your knowledge, tips and comments to win cash prizes in OLBG's World Cup tipster competition - £10,000 to be won!